The Lineup Lock Times option sets when team lineups lock each week. This applies to moving players between active slots, or between active slots and bench slots. Below are the two options available in Custom Leagues:
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Lock Individually at Scheduled Gametime: This is the default setting and is used by the majority of leagues. If selected, team owners can make moves to their weekly rosters until the scheduled kickoff time of each player's game.
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Lock at First Game of the Week: All roster moves will lock at the first game of the week, even if the first game falls on a Thursday.
NOTE: In League Manager Leagues, the League Manager may change the Lineup locktime settings up until one hour prior to the draft.